The body defends a set point — and the set point is neurological.
Decades of obesity research, from the work of Dr. Rudolph Leibel at Columbia to the set-point model later refined by Dr. Kevin Hall at the NIH, makes one thing clear: the body actively defends a weight range. Drop calories below what the brain perceives as survival and resting metabolic rate falls, hunger hormones surge, and the thermostat pulls the body back. The body does not want to get smaller. The brain is running the program.

